15 Top Cannabis Strains for Anxiety and Depression

By Leafy Mate June 5, 2023

In today’s evolving wellness landscape, cannabis is steadily gaining recognition as a therapeutic agent for various conditions. Notably, it has become an increasingly popular alternative to traditional treatments for anxiety and depression. These common mental health issues can be incapacitating, often hindering people from fully participating in their everyday lives. However, with the diverse range of cannabis strains available, one can find one that may help alleviate these conditions.

In this article, we will explore 15 top cannabis strains identified as potentially beneficial for those struggling with anxiety and depression. Each strain is unique in its properties, with varying levels of cannabinoids and terpenes believed to contribute to their potential therapeutic effects.

The Ins & Outs of Anxiety & Depression

Anxiety and depression, two prevalent mental health conditions, are complex and multifaceted disorders impacting millions worldwide. Despite their widespread occurrence, they’re often misunderstood due to their invisible nature and mental health stigma. However, unraveling these disorders’ intricacies allows us to understand better their origins, symptoms, and potential treatment pathways.

At the core, anxiety, and depression are mood disorders that alter how people feel, think, and behave. Anxiety disorders are characterized by persistent and excessive worry, while depression is primarily marked by feelings of sadness, hopelessness, and a lack of interest or pleasure in activities. It’s not uncommon for these two conditions to coexist, further complicating the individual’s experience.

Scientifically speaking, both anxiety and depression are believed to stem from a complex interplay of biological, psychological, and environmental factors. Genetics plays a significant role, with evidence suggesting that conditions like lifetime anxiety disorder can run in families. Neurobiologically, they are linked with the dysregulation of certain neurotransmitters in the brain, such as serotonin, dopamine, and norepinephrine. These chemicals are key players in mood regulation, and imbalances can contribute to the symptoms of anxiety and depression.

However, it’s not all about biology. Psychological theories propose that certain thinking styles, such as a tendency towards negative thinking or perfectionism, can make individuals more prone to these conditions. Environmental factors, such as traumatic experiences, chronic stress, or significant life changes, can also trigger the onset of anxiety and depression.

Understanding these nuances is crucial because it opens the door to various treatment options. Traditional approaches by a mental health professional may include psychological therapies like cognitive-behavioral therapy (CBT) and medications such as selective serotonin reuptake inhibitors (SSRIs). However, as our understanding of these disorders deepens, so does our repertoire of potential treatments. Recently, interest has grown in using natural therapies, including specific cannabis strains that may help alleviate depression and anxiety symptoms.

Post-traumatic stress disorder (PTSD) is a mental health condition triggered by experiencing or witnessing a terrifying event. Symptoms may include flashbacks, nightmares, severe anxiety, and uncontrollable thoughts about the event. PTSD is closely related to generalized anxiety disorder and depression, as they share many common symptoms and can often co-occur.

Like anxiety and depression, PTSD is believed to occur due to a combination of factors such as:

  1. Biological Factors: Certain brain structure and function changes are seen in individuals with PTSD. Specifically, areas of the brain involved in memory and emotion, such as the hippocampus and amygdala, are often affected.
  2. Genetic Factors: PTSD, like other mood disorders diagnosed, appears to have a genetic component. Individuals with family members who have PTSD or other mental health disorders may be more likely to develop PTSD themselves.
  3. Environmental Factors: Exposure to traumatic events such as combat, natural disasters, personal assaults, or accidents can lead to PTSD. The severity, duration, and proximity of the traumatic event are key factors influencing the likelihood of developing PTSD.

PTSD can lead to feelings of intense fear, helplessness, or horror, similar to those experienced during the traumatic event. These emotional responses can contribute to the development of depressive symptoms. Similarly, the chronic state of heightened fear and anxiety in PTSD can manifest as an anxiety disorder.

In terms of treatment, many therapeutic approaches for anxiety and depression, such as cognitive-behavioral therapy (CBT) and medications like SSRIs, can also be effective for PTSD. Additionally, exposure therapy, a form of CBT specifically designed to help people who have experienced trauma, is often used.

Recent research has also suggested that certain strains of cannabis might be beneficial in treating PTSD symptoms. This connection has led to an increased interest in understanding the potential benefits and risks of cannabis use in the context of PTSD. However, consulting a healthcare professional is essential when considering new treatment options.

How can marijuana help?

Cannabis has been increasingly recognized for its potential benefits in managing symptoms of various mental health conditions, including PTSD, anxiety, and depression. Its potential therapeutic effects are primarily attributed to the plant’s two primary cannabinoids: delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). THC is primarily responsible for the plant’s psychoactive effects, while CBD is non-psychoactive and is often associated with the plant’s potential therapeutic benefits.

  1. A study published in the Journal of Dual Diagnosis in 2016, titled “PTSD Symptom Reports of Patients Evaluated for the New Mexico Medical Cannabis Program,” investigated the effects of cannabis on PTSD symptoms. The study involved 80 psychiatric evaluations of patients applying to the New Mexico Medical Cannabis Program from 2009 to 2011. The researchers found a greater than 75% reduction in Clinician Administered Posttraumatic Scale for DSM-IV (CAPS) scores when patients were using cannabis compared to when they were not.
  2. Another study published in the Journal of Affective Disorders in 2018, titled “Cannabis Use and mental health-related Quality of Life among Individuals with depressive disorders,” examined the impact of cannabis on the quality of life among individuals with depressive disorders. The research found that, over time, cannabis use was associated with a small improvement in depression and physical health-related quality of life.

Can other mood disorders benefit from cannabis, too?

THC and CBD have been investigated for potential benefits in various mood disorders beyond anxiety and depression. However, it’s crucial to understand that research in these areas is ongoing, and the efficacy and safety of cannabis to treat mood disorders are not yet fully established. The use of cannabis for related disorders should always be under the guidance of a healthcare professional. Here’s what some of the current research says:

  1. Disruptive Mood Dysregulation Disorder (DMDD): While there’s currently little direct research on cannabis for DMDD, some studies suggest that CBD, in particular, may have the potential for treating irritability and aggression, symptoms often seen in this disorder. However, more research is needed.
  2. Bipolar II Disorder: Using cannabis in bipolar disorder is a complex issue. Some patients report using cannabis to alleviate symptoms such as anxiety and insomnia. However, research published in the journal PLoS One in 2015 found that bipolar individuals who used cannabis had a higher risk of suicide, indicating that it might worsen outcomes. More research is needed to understand these dynamics fully.
  3. Persistent Depressive Disorder (Dysthymia): Persistent depressive disorder is a long-term, chronic form of depression. While research is limited, some studies suggest that cannabis, especially strains with higher CBD content, might help alleviate depressive symptoms. However, more research is needed in this area.
  4. Seasonal Affective Disorder (SAD): SAD is a type of depression related to seasonal changes. While there’s a lack of direct research on cannabis for SAD, some individuals report that cannabis, particularly strains high in CBD, can help alleviate symptoms before they reach a major depressive disorder.
  5. Premenstrual Dysphoric Disorder (PMDD): Cannabis, particularly CBD, has been reported to help with mood swings and physical discomfort associated with PMDD. However, more research is needed to confirm these effects.
  6. Hypomanic or Manic Episodes: Using cannabis in the context of mania or hypomania is controversial as it could lead some to develop mood disorders. Some research indicates that cannabis use might increase the risk of manic symptoms in individuals with bipolar disorder. Therefore, it’s important to proceed cautiously and consult a healthcare professional.
  7. Panic Disorders: While some individuals report that certain strains of cannabis can help reduce anxiety and panic attacks, others find that cannabis can trigger these symptoms, especially strains high in THC. More research is needed to understand these effects fully.
  8. Psychotic Disorders: In general, cannabis, especially strains high in THC, is not recommended for individuals with psychotic disorders as it can potentially exacerbate symptoms and induce a psychotic episode or major depression. However, some research suggests that CBD might have antipsychotic effects. More research is needed in this area.

Which Cannabis Strains Contain the Best Terpenes for Anxiety Relief?

When it comes to anxiety relief, certain cannabis strains contain the best terpenes for anxiety. Strains like Linalool, Myrcene, and Limonene have been shown to have calming and relaxing effects, making them great options for those seeking natural anxiety relief.

Our Top 15 Strains for Relief from Anxiety & Depression

Here, we’re including a list of 15 cannabis strains that are often recommended for anxiety and depression. However, everyone’s experience with cannabis can be different, so we recommend starting low and slow. Always consult a healthcare provider or a knowledgeable dispensary professional when choosing a strain for a specific purpose.

  1. Northern Lights: This indica strain is known for its calming and relaxing effects, which may help with anxiety and promote restful sleep.
  2. Pineapple Express: A sativa-dominant hybrid that combines a gentle mood uplift with a mild body relaxant effect. It’s often used to alleviate stress and depression.
  3. Jack Herer: Named after the cannabis activist, this sativa-dominant strain is known for its uplifting and energizing effects. It’s often recommended for daytime use to help manage symptoms of depression.
  4. Green Crack: Despite its name, this is a pure cannabis strain. It’s a sativa known for its energizing effects, which can help those dealing with fatigue from depression.
  5. Girl Scout Cookies (GSC): This hybrid strain is known for its high THC content and strong effects on both the mind and body. It’s often used to help with both depression and anxiety.
  6. Amnesia Haze: This strain is a sativa with a high THC content known for its uplifting and euphoric effects, which can be helpful for individuals dealing with depression.
  7. Cannatonic: This is a high-CBD hybrid strain often used for its relaxing and mood-stabilizing effects, making it a potential option for those with anxiety or depression.
  8. OG Kush: A classic strain, OG Kush is a hybrid known for its balanced mental and physical effects. It’s often used for stress relief and mood improvement.
  9. Harlequin: This is a sativa-dominant strain high in CBD, making it a potential choice for those with anxiety seeking relief without a strong psychoactive effect.
  10. White Widow: Known for its balanced effects, this hybrid strain is often used for its mood-lifting and relaxation properties.
  11. Lemon Kush: This hybrid strain is known for its stress-relieving properties and mood-enhancing effects, which may make it a good choice for those with a mood disorder.
  12. Purple Kush: This indica strain is known for its deeply relaxing effects, which can help promote restful sleep and reduce anxiety.
  13. Super Silver Haze: A sativa-dominant strain known for its uplifting and euphoric effects, which may help combat symptoms of depression and anxiety.
  14. Cherry Pie: This hybrid strain is often used for its mood-boosting effects, which may help those dealing with depression.
  15. Bubba Kush: This indica strain is known for its relaxing and sleep-inducing effects, making it a potential choice for those dealing with anxiety, particularly if it’s causing sleep issues.

The Takeaway: Weed Strains for Mental Health

In conclusion, the world of cannabis offers a promising avenue for those seeking natural alternatives to conventional anxiety and depression treatments. The 15 cannabis strains discussed in this article reflect the diverse range of options available, each with unique properties that may assist in managing these mental health conditions.

While individual responses can vary, and it’s essential to consult healthcare professionals when considering cannabis as a treatment option, many individuals report positive experiences with these strains. As research continues to deepen our understanding of cannabis and its potential benefits, we expect to see more targeted and effective strains emerging. This exciting frontier of mental health care promises relief and well-being for many.

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